A noncytotoxic DsRed variant for whole-cell labeling
نویسندگان
چکیده
منابع مشابه
Noncytotoxic orange and red/green derivatives of DsRed-Express2 for whole-cell labeling
BACKGROUND Whole-cell labeling is a common application of fluorescent proteins (FPs), but many red and orange FPs exhibit cytotoxicity that limits their use as whole-cell labels. Recently, a tetrameric red FP called DsRed-Express2 was engineered for enhanced solubility and was shown to be noncytotoxic in bacterial and mammalian cells. Our goal was to create derivatives of this protein with diff...
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ژورنال
عنوان ژورنال: Nature Methods
سال: 2008
ISSN: 1548-7091,1548-7105
DOI: 10.1038/nmeth.1264